INGREDIENTS
BRAIN HERBS & ITS INGREDIENTS
SHANKHAPUSHPI
(Convolvulus pleuricaulis ):
Shankhapushpi (Convolvulus pleuricaulis Chois) is a perennial, prostate or sub erect spreading hairy herb, found throughout India. Important chemical principles are microphyllic acid, shankhapushpin, kaempferol-kaempferol-3-glucoside, 3, 4 dihydroxycinnamic acid, sitosterols. Neuroprotectve and intellect promoting activity implicated to free radical scavenging and antioxidant property. Herbalists believe that Shankhpushpi calms the nerves by regulating the body’s production of the stress hormones, adrenaline and cortisol. Recommended therapeutic form is fine paste of whole plant. Highly regarded as Medhya (intellect promoter).
GUDUCHI
(Tinospora cordifolia ):
Guduchi (Tinospora cordifolia (Wild) Miers) is a large glabrous, deciduous, climbing shrub of Menispermaceae family found throughout tropical India. Chemical constituents’ classes are alkaloids, diterpenoid lactones, glycosides, steroids, sesquiterpenoid, phenolics, aliphatic compounds and polysaccharides. Neuroprotective and ameliorative properties are due to their antioxidant and trace element contents. Tinospora cordifolia is known to be a rich source of trace elements (Zinc and Copper) which act as antioxidants and protects cells from the damaging effects of oxygen radicals generated during immune activation.Its root is known for its anti stress, anti-leprotic and anti-malarial activities. Tinospora cordifolia has been claimed to possess learning and memory enhancing, antioxidant, and anti-stress activity. Mechanism of cognitive enhancement is by immunostimulation and increasing the synthesis of acetylcholine, this supplementation of choline enhances the cognition. Myriad actions of Guduchi may be attributed to its antioxidant and immunomodulatory properties.
MANDUKPARNI
(Centella asiatica):
Mandukaparni (Centella asiatica Linn.) is a prostrate, stoloniferous perennial herb rooting at nodes. Major constituents are saponin (medacoside, asiaticoside, medacassoside, asiatic acid, a new triterpenic acid. They act on behaviour besides being neuroprotectives, brain growth promoter. Dendritic arborization is supposed to be the neuronal basis for improved learning and memory.
YASHTIMADHU
(Glycirrhiza glabra):
Yastimadhu (Glycirrhiza glabra Linn.) is a hardy herb or under shrub belonging to Fabaceae family. Active ingredients are glycyrrhizine, flavonones, isoflavones, glycyrrhetenic acid, six phenolic compounds. Multidimensional activities of Yashtimadhu may be attributed to glycyrrhizine and flavonones. The roots and rhizomes of Glycyrrhiza glabra is an efficient brain tonic; it increases the circulation into the CNS system and balance the sugar levels in the blood. Liquorice has significant action on memory enhancing activity in dementia, it significantly improved learning and memory on scopolamine induced dementia.
ASHWAGANDHA
(Withania Somnifera):
Ashwagandha (Withania somnifera, fam. Solanaceae) is commonly known as “Indian Winter cherry” or “Indian Ginseng”. It is one of the most important herb of Ayurveda (the traditional system of medicine in India) used for millennia as a Rasayana for its wide ranging health benefits. The biologically active chemical constituents of Withania somnifera (WS) include alkaloids (isopelletierine, anaferine, cuseohygrine, anahygrine, etc.), steroidal lactones (withanolides, withaferins) and saponins). Sitoindosides and acylsterylglucosides in Ashwagandha are anti-stress agents. Ayurveda, the traditional system of medicine practiced in India can be traced back to 6000 BC. For most of these 6000 years Ashwagandha has been used as a Rasayana. The root of Ashwagandha is regarded as tonic, aphrodisiac, narcotic, diuretic, anthelmintic, astringent, thermogenic and stimulant. Withaferin A and 3-b-hydroxy-2,3-dihydrowithanolide F isolated from Withania somnifera show promising antibacterial, antitumoral, immunomodulating and anti-inflammatory properties. Many clinical experiences showed that besides the enumerated neurological conditions, brain strokes causing paralysis and neuronal deficit also improve in the long term treatment with Ashwagandha. It is also being used in all forms of cancer including prostate and lung cancers, especially in last stages, giving the patients lot of health benefits. There are some cases of lung cancer who have refused modern therapy and recovered clinically and radiologically with the therapy of Ashwagandha.
BRAMHI
(Bacopa monniera):
Aindri (Bacopa monniera) commonly called as Brahmi belongs to Scrophulariaceae family. It is a small, creeping marshy herb grown through out India. Bacopa monniera is a saponin rich plant. Bacosides are the main active nootropic principle present in the alcoholic extract of the plant. Properties are said to be similar to that of Mandukaparni. Bacopa monniera is a well-known nootropic plant reported for its cognitive enhancer, hepatoprotective, memory enhancer and antioxidant actions. Isolation of a new saponin, a jujubogenin, named bacopasaponin G, and a new glycoside, phenylethyl alcohol was reported. Three new saponins designated as bacopasides III, IV and V isolated. It is mainly utilized in the treatment of memory and attention disorders.
JYOTISHMATI
(Celastrus panniculata):
Jyotishmati (Celastrus panniculata) is a large, woody, climbing shrub with ovate or obvovate leaves found all over India. Seeds are yellowish, ellipsoid or ovoid enclosed in a scarlet aril, Seed oil (Jyotishmati Taila) is known for Medhya action. This oil contains several terpenoids like paniculatadiol, b-sitosterol, celastrol, b-amyrin, pristimerin, but its most investigated components are its many sesquiterpenoids, dihydroagarofuran-type polyols or esters.
KUSHMANDA
(Benincasa hispida):
Kushmanda (Benincasa hispida) belonging to Cucurbitaceae an extensive trailing or climbing herb cultivated throughout the plains of India as a vegetable. The fruit, broadly cylindrical, is covered with a waxy bloom. Phytochemical analysis of Benincasa hispida shows presence of alkaloids, flavinoids, saponins and steroids. Kushmandadi Ghrita showed significant results in the management Chittodvega (anxiety disorders).
JATAMAMSI
(Nardostachys jatamamsi):
Jatamamsi (Nardostachys jatamamsi) is an erect perennial aromatic herb with long, stout, woody, greyish, rhizomatous, tail-like rootstock covered with reddish-brown hairs or tufted fibrous remains of the petioles of withered radical leaves and belongs to Valerianaceae family. Rhizome is used for medicinal purposes as it is Bhutaghna or Manasa Doshahara (relieves of psychiatric problems) and Medhya. Roots and rhizomes of N. jatamansi are used to treat hysteria, epilepsy, and convulsions. The decoction of the drug is also used in neurological disorders, insomnia and disorders of cardiovascular system. Rhizomes contain a terpenoid ester, nardostachysin I.
JATAMAMSI
(Nardostachys jatamamsi):
Jatamamsi (Nardostachys jatamamsi) is an erect perennial aromatic herb with long, stout, woody, greyish, rhizomatous, tail-like rootstock covered with reddish-brown hairs or tufted fibrous remains of the petioles of withered radical leaves and belongs to Valerianaceae family. Rhizome is used for medicinal purposes as it is Bhutaghna or Manasa Doshahara (relieves of psychiatric problems) and Medhya. Roots and rhizomes of N. jatamansi are used to treat hysteria, epilepsy, and convulsions. The decoction of the drug is also used in neurological disorders, insomnia and disorders of cardiovascular system. Rhizomes contain a terpenoid ester, nardostachysin I.
VACHA
(Acorus calamus):
Vacha (Acorus calamus) of Araceae family is a semiaquatic, perennial, aromatic herb with its rhizome being horizontal, rounded, somewhat vertically compressed, spongy and leaves grass like and sword shaped; grown all over India. Rhizome is useful part having Medhya quality. It has been used in Indian and Chinese system of medicine for hundreds of years to cure diseases especially the central nervous system (CNS) abnormalities. Active chemical principles are α-asarone, elemicine, cis-isoelemicine, cis and trans isoeugenol and their methyl ethers, camphene, P-cymene, bgurjunene, a-selinene, b-cadinene, camphor,terpinen-4-ol, aterpineol and a-calacorene, acorone, acrenone, acoragermacrone, 2-deca–4,7 dienol, shyobunones, linalool and preisocalamendiol. Acoradin, galangin, 2, 4, 5- trimethoxy benzaldehyde, 2,5- dimethoxybenzoquinone, calamendiol,spathulenol and sitosterol are also present 2. It has been proved for its analgesic and anticonvulsant, hepatoprotective, antioxidant, antimutagenic and hypothermic effects. Good in clearing speech to the children and useful in schizophrenic psycosis.
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